Health Tech Accelerator

The Health Tech Accelerator program empowers faculty and staff from the University of Pennsylvania and Penn Medicine to develop and commercialize medical devices and health technologies to advance health and health care. The program is co-sponsored by Penn Health-Tech and the Acceleration Lab at the Penn Medicine Center for Health Care Innovation.  Participating teams receive funding, hands-on advising to support development and achieve proof of concept, and access to industry experts and complementary programs to assist with engineering and design, manufacturing, regulatory guidance, quality systems, and marketing.

Penn Health-Tech and the Penn Medicine Center for Health Care Innovation invite faculty and staff from the University of Pennsylvania, Penn Medicine, and Children’s Hospital of Philadelphia (CHOP) to submit proposals for pilot funding through the Health Tech Accelerator program. The goal of this funding is to support the development of medical device and health technology projects that address important unmet medical needs and/or the translation of the technology (e.g., commercialization, licensing agreement, start-up formation). Pilot-funded projects can include early-stage technologies that do not yet qualify for support by federal agencies through later-stage technologies that are not yet mature enough for private investment. Proposals that cross departments and schools and promote sharing expertise are strongly encouraged.



2021-2022 Cohort

ALFA (A Lung for All) Ventilator: cost-efficient and compact novel mechanical ventilator

Altaios: urine-based point-of-care testing platform

BABY SEAL: promoting intrinsic sucking in cleft palate infant bottle feeding

Developing CAR T cells: novel microfluidic device producing optimized CAR T cells within 24 hours

Early Postpartum Hemorrhage Detection Software and Device: detecting a change in a mother’s circulating blood volume

Eye-V Ultrasound: ultrasound images directly at the point-of-care

Hemostatic chest tube: non-invasive balloon providing hemostasis at the bedside

Low-cost diagnostic platform: for COVID-19 and other emerging pathogens

Needle-Free Injector: precise drug delivery at variable depths

Smart Band-Aid: wound infection management hindering bacterial growth and disrupting biofilms

Smart Feeding Tube: to avoid life threatening airway complications

Additional projects supported: Predevelopment, Off-Cycle, and Sponsored Opportunities

IDEA PRIZE Engineered chewing gum for debulking biofilm and oral SARS-CoV-2: plant enzyme-based antimicrobial chewing gum for the prevention of plaque and microbial aerosol transmission


2019-2020 Cohort

Augmented Reality Surgical Navigation System: augmented reality (AR) enhanced computer assisted surgical navigation system to help surgeons navigate and accurately insert surgical implants percutaneously

Biomaterial Delivery System for Enhanced Cartilage Repair: cartilage repair intervention that localizes and directs stem cells

Eye-on-a-chip: blinking, in-vitro model of the human ocular surface

Hypknowledge: web-based sleep application that uses proprietary algorithms to provide customized recommendations for your best sleep

Improving Sensitivity of Liquid Biopsy: method for enriching targeted nucleic acid in body fluid samples to potentially provide a better way to diagnose and detect cancer in liquid biopsies

Microscopic Robot-Assisted Axon Regrowth for Rapid Repair of Peripheral Nerve Injuries: miniaturized robotic devices that bind regenerating axons and pull them to recapitulate the controlled process of axon stretch growth

Minimally Invasive Stabilization of Fractured Ribs: VATS rib fixation system capable of intrathoracic screw protection and maintenance of ideal screw-plate interface angles

MXtrodes: high resolution, low lost EEG sensors

Remotely Adjustable Pulmonary Artery Band: minimally invasive, origami-inspired pulmonary artery band for blood flow control

Stellate Ganglion Magnetic Stimulator: wearable transcutaneous magnetic stimulation device

TAIRIS: computer-vision based surgical platform for predictive analytics and intelligent guidance

Additional projects supported: Predevelopment, Off-Cycle, and Sponsored Opportunities

NEMO PRIZE Paper-based wearable biosensor for real-time diagnosis of COVID-19: Paper-based biosensor that can quickly determine the presence of SARS-CoV-2 particles from saliva and from samples from the nose and back of the throat, provides results in four minutes with high accuracy

OFF-CYCLE Rapid and Ultra-sensitive SARS-CoV-2 Antigen Detection at the Point-of-care: Novel microbubbling digital assay for ultra-sensitive detection of SARS-CoV-2 antigen for early/acute SARS-CoV-2 infection detection at the point-of-care

Predevelopment 3D Printed Pessary for Pelvic Organ Prolapse: kirigami-inspired silicone pessary that allows self-directed insertion and removal

Predevelopment Sensor for real-time detection and on-demand treatment of bacterial infections: low-cost diagnostic and therapeutics for infectious disease


2018-2019 Cohort

Avisi Technologies: Visiplate is a nanoscale aqueous shunt that seeks to lower intraocular pressure (IOP)

Cartilage replacement surgical technique: transplant instrumentation set designed to simplify meniscal and cartilage transplants and make it accessible to more surgeons

Chest Tube Inserter: chest tube with an inner obturator and an outer flange that one can use to hold and manipulate the distal end inside of the chest

Cogwear Technologies: Wearable, wireless EEG technology that monitors brain activity and provides neuroanalytics

Conforming Mask Cushion for Neonatal Resuscitation: thin, disposable interface that will sit between the face and facemask, providing a leak-free seal that places less force on the infant’s face

Electrolytic Ablation Probe: device that can apply electrochemical treatment (EChT) can offer customized ablations zones avoiding critical structures and treatment of irregularities in tumor shapes

Fistula Bypass Implant: device to collect proximal gastrointestinal secretions and ingested food and refeed materials distally, allowing patients to eat normally and remain in a non- hospital setting

Fistula Clip: an internal fixation device that can be applied via a percutaneous technique

Generic Spine Implants: vertically integrating implant fabrication

Intelligent Tutor: push technology that allows relevant educational content to be pushed to the Radiologist immediately when interpreting images, rather than the radiologist actively searching for the material while working

Limb perfusion system: ex-vivo limb perfusion system that can keep limbs alive until they are reattached or transplanted

Minimally Invasive Microcatheter: novel access system for gene therapy delivery, chemotherapy, and catheter-directed laser tumor ablation

Neuralert Technologies: asymmetry-detecting algorithm that can rapidly identify patients having a stroke

OsciFlex: medical devices for the prevention of thrombosis

Peach Pal: an effective, convenient, single-use, disposable product treatment of PPP

Prohibix: injectable hydrogel-based platform drug delivery technology designed to locally target tissue degrading enzymes to preserve cartilage, bone and synovial tissues

Small-Scale Robotics for Biofilm Removal: utilizes small-scale robots to clean biofilm infections on surfaces or difficult to access spaces

Universal Antibody Tags for Efficient Cytosolic Delivery: novel method for the efficient delivery of antibodies into the cytoplasm of cells