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Unmet Clinical Need

Liquid biopsy is challenged by the low abundance of alleles containing critical clinical information and their sequence homologies with abundant (wildtype) nucleic acids from healthy cells (low signal to noise ratio).

Proposed Healthcare Solution

An improved method for enriching targeted nucleic acid in body fluid samples to potentially provide a better way to diagnose and detect cancer in liquid biopsies

Development Stage

Clinical Testing

Funding Cycle



Haim Bau, PhD
Jinzhao Song, PhD
Erica Carpenter, MBA, PhD
Charu Aggarwal, MD, MPH


For more information on this technology, please contact Penn Center for Innovation at pciinfo@pci.upenn.edu