Universal Antibody Tags for Efficient Cytosolic Delivery

Project Information

Problem

Many intracellular targets are not susceptible to small molecule drugs because they lack natural ligands or even ligand binding sites.

Solution

A novel antibody tag that enables the efficient delivery of antibodies into the cytoplasm of cells.

Technology Type

Diagnostic

Aids with identifying the nature and cause(s) of a clinical problem or illness

Facilitator

Increases the efficacy of a clinical process or procedure

Therapeutic

Enables healing from or treatment of an illness or clinical problem

Monitor

Records/shares data as on-going surveillance of a clinical problem, process or procedure

PI/Inventor(s)

Andrew Tsourkas, PhD

Professor of Bioengineering

Penn Engineering

Michael Mitchell, PhD

Assistant Professor of Bioengineering

Penn Engineering

Cohort

2018-2019