MINT: A Multipoint Injection Technology for Intraparenchymal Gene Transfer
Efficient transduction of the entire putamen with AAV through a single procedure has been challenging. Doses of AAV required to achieve full putaminal transduction are much higher than initially thought.
The MINT systems are compatible with magnetic resonance imaging and standard surgical procedures. By increasing the number of injection sites, MINT reduces the duration of the injection procedure while improving the delivery and gene transfer efficiency.
Aids with identifying the nature and cause(s) of a clinical problem or illness
Increases the efficacy of a clinical process or procedure
Enables healing from or treatment of an illness or clinical problem
Records/shares data as on-going surveillance of a clinical problem, process or procedure